BCCT family transporter | |||||||||
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Identifiers | |||||||||
Symbol | BCCT | ||||||||
Pfam | PF02028 | ||||||||
InterPro | IPR000060 | ||||||||
TCDB | 2.A.15 | ||||||||
OPM family | 67 | ||||||||
OPM protein | 3fhx | ||||||||
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Betaine / Carnitine / Choline Transporters (BCCT) are a family of prokaryotic transport proteins that are specific for compounds containing a quaternary nitrogen atom. The BCCT proteins contain 12 transmembrane regions and are energized by proton symport. They contain a conserved region with four tryptophans in their central region[1].
The mammalian betaine transporter (SLC6A12) is regulated by NFAT5 during response to osmotic stress.[2]
This article incorporates text from the public domain Pfam and InterPro IPR000060